Trigeminal neuralgia linked to demyelination in multiple sclerosis

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The frequency of trigeminal neuralgia in multiple sclerosis patients referred to Iranian MS Association during 2004-2005

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BACKGROUND Trigeminal neuralgia (TN) is relatively frequent in multiple sclerosis (MS) patients and can be extremely disabling. Surgical interventions are less effective for the treatment of MS-related TN compared with classic TN, and higher recurrence rates are observed. OBJECTIVE To evaluate initial pain-free response (IPFR), duration of pain-free intervals (PFIs), and factors predictive of...

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Trigeminal neuralgia triggered by auditory stimuli in multiple sclerosis.

OBJECTIVES To describe a patient with a demyelinating brainstem lesion who developed right-sided trigeminal neuralgia triggered by auditory stimuli and to discuss the pathophysiological mechanisms underlying this unusual phenomenon. DESIGN Case report. SETTING Referral center. PATIENT A 27-year-old man who presented with clinical signs of a brainstem lesion developed right-sided trigemina...

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The treatment of trigeminal neuralgia in patients with multiple sclerosis using percutaneous radiofrequency rhizotomy.

BACKGROUND Trigeminal neuralgia (TN) has a higher incidence among patients with multiple sclerosis (MS) than in the general population. This cohort of MS patients with TN presents a series of management challenges including poor tolerance of antineuralgic medications and occasional bilateral presentation. We analyzed our surgical series of MS patients presenting with TN who were treated with pe...

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Misoprostol as a therapeutic option for trigeminal neuralgia in patients with multiple sclerosis.

Case 1 reports of a 65-year-old female patient with a 32-year history of MS and a 4-year history of TN (V2 only). Further findings were a hemiparesis and hemiplegia lasting 1 year and a history of hypertension. She was suffering from pain attacks with a visual analog scale (VAS) of 10/10, which made eating impossible. The bouts appeared 20 times per day and lasted approximately 10 minutes. Duri...

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ژورنال

عنوان ژورنال: Nature Reviews Neurology

سال: 2020

ISSN: 1759-4758,1759-4766

DOI: 10.1038/s41582-020-0356-0